Study on the Oxidant and Antioxidant Status in Vitiligo Patients

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Comparison of oxidant-antioxidant status in patients with vitiligo and healthy population.

BACKGROUND Vitiligo is a well-recognized pigmentary disorder of the skin and /or mucous membrane characterized by circumscribed ivory or chalky white macules devoid of identifiable melanocytes. The pathogenesis of vitiligo is complex and still not well understood. According to autocytotoxic hypothesis, oxidative stress has been suggested to be the initial pathogenic event in melanocyte degenera...

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The altered aggregation of proteins in non-native conformation is associated with endoplasmic reticulum derangements, mitochondrial dysfunction and excessive production of reactive oxygen species. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary systemic vasculopathy, caused by NOTCH3 mutations within the receptor extracel...

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ژورنال

عنوان ژورنال: The Egyptian Journal of Hospital Medicine

سال: 2007

ISSN: 2090-7125

DOI: 10.21608/ejhm.2007.17672